In 1887, a Romanian chemist named Lazar Edeleanu first synthesized amphetamines at the University of Berlin. However, amphetamine was not used for therapeutic purposes until the 1920s, when Gordon A. Alles re-synthesized the substance for the treatment of asthma, hay fever and the common cold. In 1885, the Japanese chemist Nagai Nagayoshi synthesized methamphetamine, but methamphetamine use did not gain momentum until a few decades later.
Law enforcement agencies saw an increase in methamphetamine laboratories, where methamphetamine was created with pseudoephedrine, an over-the-counter decongestant. In the 1980s, the United States began to tighten regulations on the sale and use of ephedrine, a pharmaceutical precursor used to manufacture crystalline methamphetamine. This gives users a rapid and intense high, making crystalline methamphetamine more addictive and potentially more harmful than other forms of methamphetamine. While recent data indicate that only 0.6% of the U.S.
population uses methamphetamine in any given year, trends show a significant increase in overdose deaths related to stimulant drugs such as methamphetamine in recent years. However, some people have continued to produce methamphetamine using alternative methods, such as cooking P2P methamphetamine. Although crystalline methamphetamine is reputed to be an American street drug from the late 20th century, its origins date back to Japan in the late 19th century. However, California began to increase methamphetamine production in small laboratories spread across several locations, becoming the country's largest producer of methamphetamine.
A Japanese chemist first synthesized methamphetamine, also called methamphetamine, crank, crystalline methamphetamine or speed, from another stimulant in 1893.Many methamphetamine addicts have rotten teeth, a condition known as methamphetamine (mouth), and experience severe weight loss. However, methamphetamine is otherwise an illegal drug, since both cooking methamphetamine and using it recreational are very dangerous. At that time, Mexican drug cartels began supplying chefs with ephedrine and the consumption of crystalline methamphetamine took off. In the 1980s, after the federal government began regulating the key chemical used to produce methamphetamine, cooks who supplied the drug to motorcycle gangs discovered that the ephedrine in over-the-counter cold medicines could be used to create crystalline methamphetamine.
In 1919, a young protégé from Nagai named Akira Ogata discovered a new method for synthesizing the crystalline form of the new stimulant, giving the world crystalline methamphetamine. The CMA is a 12-step approach for methamphetamine addicts to receive appropriate support and companionship in their recovery. But since then, methamphetamine has become an illicit phenomenon in family methamphetamine laboratories, a total addiction and a series of physical and psychological side effects.